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Pronunciation: meg'a-kar'e-o-sit

Definition: A large cell (as much as 100 mcm in diameter) with a polyploid nucleus that is usually multilobed; megakaryocytes are normally present in bone marrow, not in the circulating blood, and give rise to blood platelets.

Synonym(s): megacaryocyte, megalokaryocyte, thromboblast

[mega- + G. karyon, nut (nucleus), + kytos, hollow vessel (cell)]

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© Copyright 2018 Wolters Kluwer. All Rights Reserved. Review Date: Sep 19, 2016.