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Medical Term:

medial forebrain bundle


Definition: a fiber system coursing longitudinally through the lateral zone (area) of the hypothalamus, connecting the latter reciprocally with the midbrain tegmentum and with various components of the limbic system; it also carries fibers from cell groups containing norepinephrine and serotonin in the brainstem to the hypothalamus and cerebral cortex, as well as dopamine-carrying fibers from the substantia nigra to the caudate nucleus and putamen.

Synonym(s): fasciculus medialis telencephaliTA

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