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Marburg disease


Definition: infection with an unusual rhabdovirus composed of RNA and lipid, tentatively assigned to the family of Filoviridae. Virus is “pantropic” and affects most organ systems. The disease, characterized by a prominent rash and hemorrhages in many organs, is often fatal. First seen among laboratory workers in Marburg, Germany, exposed to African green monkeys. Some interhuman spread has been observed. Attempts to isolate virus should be done only in high-security laboratories.

Synonym(s): Marburg virus disease

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© Copyright 2018 Wolters Kluwer. All Rights Reserved. Review Date: Sep 19, 2016.