Pronunciation: man'os-fos'fat i-som'er-as
Definition: An enzyme that catalyzes the reversible conversion of d-mannose 6-phosphate to d-fructose 6-phosphate; a key step in the synthesis of mannose derivatives, as well as the entry of mannose into the central pathways of carbohydrate metabolism.
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Examples: glitazone, GI cocktail, etc.