Pronunciation: man wil'yam-son
Definition: an operation performed on experimental animals (dogs) in research on peptic ulcer, the duodenum with its alkaline secretions being transplanted into the ileum and the cut end of the jejunum anastomosed to the pylorus; the animals develop ulcers in the jejunum, which directly receives the gastric juice.
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Examples: glitazone, GI cocktail, etc.