Pronunciation: man'drel, man'dril
- The shaft or spindle to which a tool is attached and by means of which it is rotated.
- In dentistry, an instrument used in a handpiece to hold a disc, stone, or cup used for grinding, smoothing, or finishing.
[G. mandra, a stable; the bed in which a ring's stone is set]
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Examples: glitazone, GI cocktail, etc.