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Medical Term:

major histocompatibility complex


a group of linked loci, collectively termed H-2 complex in the mouse and HLA complex in humans, which codes for cell-surface histocompatibility antigens and is the principal determinant of tissue type and transplant compatibility.

See Also: human leukocyte antigens, under antigen

© Copyright 2017 Wolters Kluwer. All Rights Reserved. Review Date: Sep 19, 2016.