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macrophagic myofascitis


Definition: an inflammatory myopathy detected in patients with diffuse arthromyalgias and severe fatigue; characterized by muscle infiltration by granular periodic acid-Schiff reagent–positive macrophages and lymphocytes. The inclusions detected in the macrophages have been identified as aluminum hydroxide, an immunostimulatory compound used as a vaccine adjuvant.

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© Copyright 2018 Wolters Kluwer. All Rights Reserved. Review Date: Sep 19, 2016.