Skip to Content
Medical Term:

lysyl hydroxylase

 

Definition: an enzyme that acts on specific lysyl residues in certain proteins (collagens) with a-ketoglutarate and O2 to produce ?-hydroxylysyl residues, succinate, and CO2; this enzyme, which requires Fe2+ and ascorbate, is deficient in Ehlers-Danlos syndrome type VI.

Synonym(s): lysyl 2-oxoglutarate dioxygenase

© Copyright 2016 Wolters Kluwer. All Rights Reserved. Review Date: Sep 19, 2016.
Hide