Definition: a comparatively large dose given at the beginning of treatment to start getting the effect of a drug, especially one with slow clearance, thus requiring a long period to achieve stable blood levels without a high initial dose.
Synonym(s): initial dose
Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.
© Copyright 2018 Wolters Kluwer. All Rights Reserved. Review date: Sep 19, 2016.
Search Stedman's Medical Dictionary
Examples: glitazone, GI cocktail, etc.