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Definition: a comparatively large dose given at the beginning of treatment to start getting the effect of a drug, especially one with slow clearance, thus requiring a long period to achieve stable blood levels without a high initial dose.

Synonym(s): initial dose

Further information

Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.

© Copyright 2018 Wolters Kluwer. All Rights Reserved. Review date: Sep 19, 2016.

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