Definition: A malignant neoplasm of adults that occurs especially in the retroperitoneal tissues and the thigh, usually deep in the intermuscular or periarticular planes; histologically, liposarcoma is a large tumor that may be composed of well-differentiated fat cells or may be dedifferentiated, either myxoid, round-celled, or pleomorphic, usually in association with a rich network of capillaries; recurrences are common, and dedifferentiated liposarcoma metastasizes to the lungs or serosal surfaces.
[lipo- + sarx, flesh, + -oma, tumor]
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