- A thread, wire, fillet, or the like, tied tightly around a blood vessel, the pedicle of a tumor, or other structure to constrict it.
- In orthodontics, a wire or other material used to secure an orthodontic attachment or tooth to an archwire.
[L. ligatura, a band or tie, fr. ligo, to tie]
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Examples: glitazone, GI cocktail, etc.