Pronunciation: lig'and, li'gand
- Any individual atom, group, or molecule attached to a central metal ion by multiple coordinate bonds, the porphyrin portion of heme, the corrin nucleus of the B12 vitamins.
- An organic molecule attached to a tracer element, a radioisotope.
- A molecule that binds to a macromolecule, a ligand binding to a receptor.
- The analyte in competitive binding assays, such as radioimmunoassay.
- An atom or group covalently attached to a specified carbon atom in an organic molecule.
[L. ligo, to bind]
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Examples: glitazone, GI cocktail, etc.