Definition: a gene that produces a genotype that leads to death of the organism before reproduction is possible or precludes reproduction; for a recessive gene the homozygous or hemizygous state is lethal.
© Copyright 2018 Wolters Kluwer. All Rights Reserved. Review date: Sep 19, 2016.
Search Stedman's Medical Dictionary
Examples: glitazone, GI cocktail, etc.