Definition: the dose of a chemical or biological preparation (a bacterial exotoxin or a suspension of bacteria) that is likely to cause death; it varies in relation to the type of animal and the route of administration; when followed by a subscript (generally “LD50” or median lethal dose), it denotes the dose likely to cause death in a certain percentage (50%) of the test animals; median lethal dose is LD50, absolute lethal dose is LD100, and minimal lethal dose is LD05.
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Examples: glitazone, GI cocktail, etc.