Definition: A fairly well-circumscribed discrete focus of granulomatous inflammation, caused by Mycobacterium leprae, which consists chiefly of an accumulation of large mononuclear phagocytic cells in which the cytoplasm seems finely vacuolated (foam cells); the foamlike character of the macrophages is related to the engulfing of numerous acid-fast organisms.
[G. lepros, scaly, + -oma, tumor]
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