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Medical Term:

Langerhans cells

Pronunciation: lahng′ĕr-hahnz


  1. dendritic clear cells in the epidermis, containing distinctive granules that appear rod- or racket-shaped in section, but lacking tonofilaments, melanosomes, and desmosomes; they carry surface receptors for immunoglobulin (Fc) and complement (C3), and are believed to be antigen fixing and processing cells of monocytic origin; active participants in cutaneous delayed hypersensitivity.
  2. cells seen in eosinophilic granuloma and lymphoma of the lungs.

Synonym(s): interdigitating dendritic cells

© Copyright 2017 Wolters Kluwer. All Rights Reserved. Review Date: Sep 19, 2016.