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Langerhans cell histiocytosis

Pronunciation: lahng'er-hahnz

Definition: a set of closely related disorders unified by a common proliferating element, the Langerhans cell. Three overlapping clinical syndromes are recognized: a single site disease (eosinophilic granuloma), a multifocal unisystem process (Hand-Schuller-Christian syndrome), and a multifocal, multisystem histiocytosis (Letter-Siwe syndrome.) Formerly this process was known as histiocytosis X.

Synonym(s): histiocytosis X

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© Copyright 2017 Wolters Kluwer. All Rights Reserved. Review Date: Sep 19, 2016.
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