Definition: Fibrous network of intermediate filaments associated with the nucleoplasmic aspect of the inner membranes of cell nuclei, composed of polypeptides of varying molecular weights (60,000–80,000) and classified as A, B, C, and upward, on the basis of physical properties; the phosphorylation of lamins is associated with mitosis and the breakdown of the nuclear envelope.
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Examples: glitazone, GI cocktail, etc.