Congenital heart disease in which the atrial situs is normal (i.e., solitus), but the position of the ventricles are inverted, and the connection of the great arteries discordant with l-position of the aorta. In l-looping, the aorta typically arises anteriorly from the right ventricle, and the pulmonary trunk arises posteriorly from the left ventricle.
Synonym(s): criss-cross heart, transposition of the great arteries
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