Definition: an explanation for the bilateral, and earlier, occurrence of hereditary retinoblastoma; if one tumor suppressor gene is mutated by inheritance, only one somatic mutation is needed inactivate the other allele. In the sporadic form, two mutations, which inactivate each allele, are necessary.
[Alfred G. Knudsen, contemporary U.S. geneticist]
Disclaimer: This site is designed to offer information for general educational purposes only. The health information furnished on this site and the interactive responses are not intended to be professional advice and are not intended to replace personal consultation with a qualified physician, pharmacist, or other healthcare professional. You must always seek the advice of a professional for questions related to a disease, disease symptoms, and appropriate therapeutic treatments.
Search Stedman's Medical Dictionary
Examples: glitazone, GI cocktail, etc.
© Copyright 2017 Wolters Kluwer. All Rights Reserved. Review Date: Sep 19, 2016.