Definition: Classification of patients with acute myocardial infarction according to the severity of concomitant signs of heart failure to estimate mortality risk.. Class I: no heart failure, Class II: pulmonary rales, elevated jugular venous pulse or S3 gallop present, Class III: frank pulmonary edema usually with significant hypoxia, Class IV: cardiogenic shock with significant hypotension. In the original report, Killip class I was associated with a mortality of 6%, while Killip class IV was associated with a 67% mortality rate.
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