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killer cells


Definition: cytotoxic cells involved in antibody-dependent cell-mediated immune responses; they possess receptors for the Fc portion of IgG molecules that lyse or damage IgG-coated target cells without mediation of complement. They are not MHC restricted.

See: antibody-dependent cell-mediated cytotoxicity, CD8

Synonym(s): K cell2, null cells1

See Also: natural killer cells

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© Copyright 2018 Wolters Kluwer. All Rights Reserved. Review Date: Sep 19, 2016.