Pronunciation: kil'e-yon'i fish'er
procedure for the extension of the carbon atom chain of aldoses by treatment with cyanide; hydrolysis of the cyanohydrins followed by reduction of the lactone yields the homologous aldose; with this method, d-glucose and d-mannose can be synthesized from d-arabinose.
Synonym(s): Kiliani-Fischer reaction
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Examples: glitazone, GI cocktail, etc.