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keratosis follicularis


Definition: an autosomal dominant disorder characterized by eruption, beginning usually in late childhood, in which keratotic papules originating from both follicles and interfollicular epidermis of the trunk, face, scalp, and axillae become crusted and verrucous; the papules are often intensely pruritic. Microscopically, dyskeratotic cells termed corps ronds are seen in the epidermis. Longitudinal nail bands are frequent.

Synonym(s): Darier disease

Further information

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© Copyright 2018 Wolters Kluwer. All Rights Reserved. Review date: Sep 19, 2016.