Definition: Surgical alteration of refractive error by changing the shape of a deep layer of the cornea: the anterior lamella is peeled back, frozen, and recarved on its back surface on a lathe; some of the corneal stroma can be removed from the bed with a laser or a knife.
[coinage, prob. fr. G. keras (kerat-), horn, cornea, + smileusis, carving]
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Examples: glitazone, GI cocktail, etc.