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keratan sulfate

Pronunciation: ker'a-tan sul'fat

Definition: A type of sulfated mucopolysaccharide containing d-galactose in place of the uronic acid of hyaluronic acid or chondroitin; also containing unsulfated and 6-sulfated N-acetyl-d-glucosamine; found in cartilage, bone, connective tissue, the cornea, aorta, and in the intervertebral disks; accumulates in Morquio syndrome; keratan sulfate I is abundant in cornea and is attached to a protein via an asparaginyl residue; keratan sulfate II is found in loose connective tissue and bone and is linked to a seryl or threonyl residue.

Synonym(s): keratosulfate

Further information

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© Copyright 2018 Wolters Kluwer. All Rights Reserved. Review date: Sep 19, 2016.