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Kartagener syndrome

Pronunciation: kahr-tag'e-ner

Definition: complete situs inversus associated with bronchiectasis and chronic sinusitis associated with ciliary dysmotility and impaired ciliary mucous transport in the respiratory epithelium. The mechanism of the reversal of laterality remains an enigma, but it appears to be strictly an abolition (indifference) of laterality rather than a true reversal. Autosomal recessive inheritance with variable penetrance.

Synonym(s): Kartagener triad, Zivert syndrome

See Also: immotile cilia syndrome

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© Copyright 2017 Wolters Kluwer. All Rights Reserved. Review Date: Sep 19, 2016.
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