Definition: a member of a particular family (JAK) of tyrosine kinases involved in cytokine receptor signaling. Mutations in JAK3 on chromosome 19p cause autosomal recessive severe combined immunodeficiency [MIM*600173]. JAK1 and JAK2 are mapped to the short arms of chromosomes 1 and 9, respectively.
[Janus, Roman god of doorways, depicted with two faces looking in opposite directions]
Disclaimer: This site is designed to offer information for general educational purposes only. The health information furnished on this site and the interactive responses are not intended to be professional advice and are not intended to replace personal consultation with a qualified physician, pharmacist, or other healthcare professional. You must always seek the advice of a professional for questions related to a disease, disease symptoms, and appropriate therapeutic treatments.
Search Stedman's Medical Dictionary
Examples: glitazone, GI cocktail, etc.
© Copyright 2017 Wolters Kluwer. All Rights Reserved. Review Date: Sep 19, 2016.