Skip to Content
Medical Term:


Pronunciation: i'so-im'yu-ni-za'shun

Definition: Development of a significant titer of specific antibody as a result of antigenic stimulation with material contained on or in the red blood cells of another individual of the same species; isoimmunization is likely to occur when an Rh-negative person is treated with a transfusion of Rh-positive blood from another human being, or an Rh-negative woman has a pregnancy in which the fetus inherits Rh-positive red blood cells.

© Copyright 2016 Wolters Kluwer. All Rights Reserved. Review Date: Sep 19, 2016.