isocitrate dehydrogenase

Definition: one of two enzymes that catalyze the conversion of threo-d_s-isocitrate, the product of the action of both aconitase and isocitrate lyase, to a-ketoglutarate (2-oxoglutarate) and CO₂; one of the isozymes uses NAD+ (participating in the tricarboxylic acid cycle), whereas the other uses NADP+.

Synonym(s): isocitric acid dehydrogenase, oxalosuccinic carboxylase

Further information

Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.

© Copyright 2018 Wolters Kluwer. All Rights Reserved. Review date: Sep 19, 2016.

Medical Disclaimer