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isochromosome

Pronunciation: i'so-kro'mo-som

Definition: A chromosomal aberration that arises as a result of transverse rather than longitudinal division of the centromere during meiosis; two daughter chromosomes are formed, each lacking one chromosome arm but with the other doubled.

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© Copyright 2018 Wolters Kluwer. All Rights Reserved. Review date: Sep 19, 2016.

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