Definition: symbolized as G/2 or I and set equal to 0.5Smizi2, where mi equals the molal concentration and zi the charge of each ion present in solution; if molar concentrations (ci) are used instead of molality (and the solution is dilute), then I = 0.5(1/?o)Scizi2 where ?o is the density of the solvent; a number of biochemically important events (protein solubility and rates of enzyme action) vary with the ionic strength of a solution.
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Examples: glitazone, GI cocktail, etc.
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