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intrinsic factor

 

Definition: a small mucoprotein (MW about 45,000) secreted by the neck cell of the gastric glands and required for adequate absorption of vitamin B12 and other cobalamins; deficiency results in pernicious anemia.

Synonym(s): Castle intrinsic factor

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© Copyright 2017 Wolters Kluwer. All Rights Reserved. Review Date: Sep 19, 2016.
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