Definition: the major interferon made by virus-induced leukocytes; several different subtypes exist that are elaborated by leukocytes in response to viral infection or to stimulation with double-stranded RNA. There are 14 genes on the short arm of chromosome 9 that code for these substances in humans. IFN-a-2A and -2B are protein products made by recombinant DNA techniques and are used as antineoplastic agents.
Synonym(s): leukocyte interferon
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Examples: glitazone, GI cocktail, etc.