Definition: a specially constructed microscope in which the entering light is split into two beams that pass through the specimen and are recombined in the image plane where the interference effects make the transparent (invisible) refractile object details become visible as intensity differences; permits measurements of light retardation, index of refraction, and thickness and mass of specimen; it is useful in the examination of living or unstained cells.
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Examples: glitazone, GI cocktail, etc.