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Medical Term:

insulin resistance


Definition: diminished effectiveness of insulin in lowering plasma glucose levels, arbitrarily defined as a daily requirement of at least 200 units of insulin to prevent hyperglycemia or ketosis; usually due to binding of insulin or insulin receptor sites by antibodies; associated with obesity, ketoacidosis, and infection.

See Also: metabolic syndrome

© Copyright 2016 Wolters Kluwer. All Rights Reserved. Review Date: Sep 19, 2016.