infantile neuroaxonal dystrophy
Definition: a rare, familial disorder of early childhood manifested as progressive psychomotor deterioration, increased reflexes, positive Babinski sign, hypotonia, and progressive blindness. Pathologically, eosinophilic spheroids of swollen axoplasm are found in various central nervous system nuclei.
© Copyright 2018 Wolters Kluwer. All Rights Reserved. Review date: Sep 19, 2016.
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