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immunophilins

Pronunciation: im'yu-no-fil'inz

Definition: High-affinity receptor proteins in the cytoplasm that combine with immunosuppressant drugs leading to rotamase inhibition and, in T cells, thus to interruption of cell activation.

[immune + G. philos, fond, + in]

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© Copyright 2017 Wolters Kluwer. All Rights Reserved. Review Date: Sep 19, 2016.
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