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Medical Term:

immunologic tolerance


Definition: lack of immune response to antigen. Theories of tolerance induction include clonal deletion and clonal anergy. In clonal deletion, the actual clone of cells is eliminated whereas in clonal anergy the cells are present but nonfunctional.

Synonym(s): immunotolerance, nonresponder tolerance

© Copyright 2016 Wolters Kluwer. All Rights Reserved. Review Date: Sep 19, 2016.