Definition: a sensitizing, complement-fixing, hemolytic antibody formed in an animal as the result of parenteral administration of red blood cells or whole blood from another species; immune hemolysin may also be formed in human beings who are transfused with human blood that is antigenic in the recipient, the formation of anti-Rh antibody in an Rh-negative person who is treated with Rh-positive red blood cells.
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Examples: glitazone, GI cocktail, etc.