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immune complex glomerulonephritis

 

Definition: immune complexes are deposited in the renal glomerulus where they bind complement and initiate an inflammatory process, attracting neutrophils and macrophages, resulting in an alteration of the basement layer of the kidney. The disease state can lead to ultimate destruction of the glomerulus and renal failure.

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© Copyright 2018 Wolters Kluwer. All Rights Reserved. Review date: Sep 19, 2016.

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