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imatinib

Pronunciation: im-a-tin'ib

Definition: An oral agent important in the treatment of chronic myeloid leukemia and gastrointestinal stromal tumors; a specific inhibitor of the Philadelphia reciprocal chromosome translocation–created protein tyrosine kinase enzyme, which works by blocking rapid growth of the mutant clone of tumor cells.

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© Copyright 2018 Wolters Kluwer. All Rights Reserved. Review date: Sep 19, 2016.

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