Definition: An oral agent important in the treatment of chronic myeloid leukemia and gastrointestinal stromal tumors; a specific inhibitor of the Philadelphia reciprocal chromosome translocation–created protein tyrosine kinase enzyme, which works by blocking rapid growth of the mutant clone of tumor cells.
Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.
© Copyright 2018 Wolters Kluwer. All Rights Reserved. Review date: Sep 19, 2016.
Search Stedman's Medical Dictionary
Examples: glitazone, GI cocktail, etc.