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Medical Term:

human leukocyte antigens


Definition: system designation for the major histocompatibility complex gene products of at least four linked loci (A, B, C, and D) and a number of subloci on the sixth human chromosome that have been shown to have a strong influence on human allotransplantation, transfusions in refractory patients, immune responsiveness to certain antigens, and certain disease associations; autosomal dominant inheritance.

See: major histocompatibility complex

© Copyright 2016 Wolters Kluwer. All Rights Reserved. Review Date: Sep 19, 2016.