Hill criteria of evidence
a set of epidemiologic criteria that help to indicate whether a statistically significant relationship obtained in epidemiologic and other studies is causal. The criteria are consistency, specificity, strength, dose-response relationship, temporality, biologic plausibility, coherence, and capability of experimental confirmation. Temporality is the only absolute criterion: the putative cause must precede the effect in time.
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Examples: glitazone, GI cocktail, etc.