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hexosaminidase B


Definition: a hydrolytic enzyme that acts on ganglioside GM1, producing ganglioside GM1 and galactose, as well as on globoside, producing N-acetylgalactosamine and trihexosylceramide; a deficiency of this enzyme is associated with Sandhoff disease.

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© Copyright 2017 Wolters Kluwer. All Rights Reserved. Review Date: Sep 19, 2016.