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Herxheimer reaction

Pronunciation: herks'hi-mer

Definition: an inflammatory reaction in syphilitic tissues (skin, mucous membrane, nervous system, or viscera) induced in certain cases by specific treatment with arsphenamine (Salvarsan), mercury, or antibiotics; believed to be due to a rapid release of treponemal antigen with an associated allergic reaction in the patient.

Synonym(s): Jarisch-Herxheimer reaction

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© Copyright 2017 Wolters Kluwer. All Rights Reserved. Review Date: Sep 19, 2016.
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