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herpes simplex encephalitis

 

Definition: the most common acute encephalitis, caused by HSV-1; affects people of any age; preferentially involves the inferomedial portions of the temporal lobe and the orbital portions of the frontal lobes; pathologically, severe hemorrhagic necrosis is present along with, in the acute stages, intranuclear eosinophilic inclusion bodies in the neurons and glial cells.

Synonym(s): acute inclusion body encephalitis, herpes encephalitis

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© Copyright 2018 Wolters Kluwer. All Rights Reserved. Review date: Sep 19, 2016.

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