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hemoglobin E


Definition: an abnormal Hb with a single ß chain substitution, molecular formula a2226Glu?Lys, common in Southeast Asia, especially Thailand; heterozygotes are asymptomatic with 35–45% Hb E; homozygotes have mild to moderate hemolytic anemia with 90–100% Hb E and the remainder Hb F.

Further information

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© Copyright 2018 Wolters Kluwer. All Rights Reserved. Review date: Sep 19, 2016.