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hemoglobin Chesapeake

 

Definition: an abnormal hemoglobin with a single a-chain substitution, molecular formula a292Arg?Leuß2A; heterozygotes have polycythemia, apparently to compensate for the increased oxygen affinity of this Hb, resulting in decreased liberation of oxygen in the tissues.

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© Copyright 2018 Wolters Kluwer. All Rights Reserved. Review date: Sep 19, 2016.

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